thrombolytic therapy for cerebral vein thrombosis in antiphospholipid syndrome secondary to systemic lupus erythematosus

Authors

hamid noshad department of nephrology, sina hospital, tabriz university of medical sciences, tabriz, iran

mehrzad hajialilo department of rheumatology, imam reza hospital, tabriz university of medical sciences, tabriz, iran

reza mohammadian department of interventional neurology, tabriz university of medical sciences, tabriz, iran

ali reza khabbazi department of rheumatology, imam reza hospital, tabriz university of medical sciences, tabriz, iran

abstract

a 20-year-old woman was admitted to a gynecology hospital in her 6th month of pregnancy for high blood pressure and tonic-clonic seizure. primary diagnosis was eclampsia, and for that reason she underwent cesarean section. she also had headache on frontal and parietal areas without nausea or vomiting. there was not a focal neurological sign. rheumatology consultation was requested. systemic lupus erythematosus and secondary antiphospholipid (aps) was confirmed. the patient had headache that continued several days after cesarean section, therefore, brain magnetic resonance imaging (mri) and magnetic resonance venography (mrv) were performed, and cerebral vein thrombosis was documented. distal segment of right lateral sinus and sigmoid sinus were not appeared in brain mrv. abnormal hypersignal intensity of right lateral sinus/coronal t2 was detected. thrombolytic therapy with 20 mg tissue plasminogen activator on right sigmoid and transverse sinus was performed by an interventional neurologist. after this procedure, the patient#s headache healed and she was discharged in a good condition.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

Thrombolytic Therapy for Cerebral Vein Thrombosis in Antiphospholipid Syndrome Secondary to Systemic Lupus Erythematosus

A 20-year-old woman was admitted to a Gynecology Hospital in her 6th month of pregnancy for high blood pressure and tonic-clonic seizure. Primary diagnosis was eclampsia, and for that reason she underwent cesarean section. She also had headache on frontal and parietal areas without nausea or vomiting. There was not a focal neurological sign. Rheumatology consultation was requested. Systemic lup...

full text

Thrombolytic Therapy for Cerebral Vein Thrombosis in Antiphospholipid Syndrome Secondary to Systemic Lupus Erythematosus

A 20-year-old woman was admitted to a Gynecology Hospital in her 6(th) month of pregnancy for high blood pressure and tonic-clonic seizure. Primary diagnosis was eclampsia, and for that reason she underwent cesarean section. She also had headache on frontal and parietal areas without nausea or vomiting. There was not a focal neurological sign. Rheumatology consultation was requested. Systemic l...

full text

Thrombolytic therapy at systemic lupus onset with secondary antiphospholipid syndrome

Strokes are a major cause of disability in systemic lupus erythematosus (SLE). Classical neurological manifestations are rare at onset. The use of thrombolytic therapy improves clinical outcome in eligible stroke patients who present early. Modern imaging modalities augment decision making. This 37-year-old woman presented with an acute stroke with National Institute of Health stroke scale 10. ...

full text

Libman-Sacks endocarditis in patients with systemic lupus erythematosus with secondary antiphospholipid syndrome

Background: Libman-Sacks endocarditis (LSE) is characterized by sterile lesions that commonly affect the aortic and mitral heart valves. Antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE) have been associated with LSE. Cardiac manifestations including LSE could be interrelated with other manifestations and early diagnosis could help in preventing further complications. Case...

full text

G20210A homozygosity in antiphospholipid syndrome secondary to systemic lupus erythematosus.

2. Morse B, Giuliani D, Nussbaum M. Quantitation of platelet-associated IgG by radial immunodiffusion. Blood 1981; 57:809-11. 3. George JN. Platelet immunoglobulin G: its significance for the evaluation of thrombocytopenia and for understanding the origin of alpha-granule proteins. Blood 1990; 76:859-70. 4. Robinson MSC, Mackie IJ, Machin SJ, Savidge GF, Harrison P. Dense granules non-specifica...

full text

My Resources

Save resource for easier access later


Journal title:
iranian journal of medical sciences

جلد ۳۷، شماره ۱، صفحات ۵۸-۰

Keywords

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023